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Cialis (Tadalafil) is used to treat erectile dysfunction and benign prostatic hyperplasia (enlarged prostate). It is used to treat symptoms of benign prostatic hyperplasia, including difficulty urinating, and to reduce symptoms associated with the condition. It is also used to treat the symptoms of pulmonary arterial hypertension and to treat symptoms of high blood pressure in the lungs (angina). Cialis is an oral drug that increases the amount of a blood vessel in your penis. This increased blood flow helps to achieve and maintain an erection. Cialis works by relaxing the muscles in your penis, allowing blood to flow into your penis when you are sexually excited. It may also help treat pulmonary arterial hypertension by relaxing the muscles in your lungs and reducing pulmonary hypertension. Cialis belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It works by increasing blood flow to the penis, helping men to achieve and maintain an erection. Cialis is available in a generic form and is typically taken as a single daily dose. It should be taken on an empty stomach, at least 30 minutes before sexual activity. Cialis can cause side effects such as headache, nausea, and dizziness. It is important to note that Cialis should not be taken by women and children, and it should not be taken by men who are pregnant or breastfeeding. Cialis should not be used by people who are allergic to tadalafil or any other ingredients in Cialis or have had an allergic reaction to it. Cialis can also cause a temporary erection that lasts longer than 4 hours. If this happens, it is important to consult your doctor before using Cialis. It is important to note that Cialis should not be taken by women and children, and it should only be taken as needed before the anticipated sexual activity. It is also important to note that this is not a complete list of Cialis side effects, but you should speak to your doctor or pharmacist if you experience any unusual symptoms. If you experience any side effects or have any concerns, you should contact a doctor right away. Cialis is available in tablet form, and the dosage is based on your medical condition. Cialis is only available in a small number of countries, so it is important to talk to your doctor about any other medications you are taking. Cialis is not recommended for use by women who are pregnant or may become pregnant. It is also not recommended for use by children and adolescents under the age of 18 years. Cialis may cause dizziness or lightheadedness when standing up. If this happens, you should avoid driving or operating machinery until you know how Cialis affects you. Cialis should not be used by children under the age of 18 years. Cialis should not be used by women who are pregnant or may become pregnant. It is important to note that Cialis can cause a temporary erection that lasts longer than 4 hours. Cialis should not be used by children and adolescents under the age of 18 years. Cialis should not be used by women and women who are pregnant or may become pregnant. It is important to note that Cialis is not approved by the FDA for use in women. Cialis should not be used for women and children, and it should only be used under the advice and supervision of a doctor. Cialis is available in tablets and oral suspensions. It is important to speak with your doctor before taking Cialis, as it may cause side effects. Cialis is not approved for use in children under the age of 18 years.

Cialis (tadalafil) Uses

Cialis (tadalafil) is used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (enlarged prostate). It is also used to treat symptoms of benign prostatic hyperplasia (water retention). It may also be used to treat pulmonary arterial hypertension and to reduce symptoms associated with the condition. Cialis may also be used to treat symptoms of pulmonary arterial hypertension. It works by relaxing blood vessels in the lungs, which increases blood flow to the lungs.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Described below are the key drug-food interactions associated with Cialis.

Key drug-food interactions to be aware of: Cialis (tadalafil) can amplify tadalafil's blood pressure-lowering effects, which can reduce how the medication will act in the body. To ensure that the interaction is not affecting your daily life, take smaller amounts of Cialis while consuming it with T sprinkle (raw tadalafil).

To maintain a consistent blood pressure-lowering effect, do not take Cialis more than once a day. This can increase the risk of side effects. Take Cialis less often than other medications used to improve blood pressure:

  • Ketoconazole, used to manage fungal infection: Cialis can enhance the blood pressure-lowering effects of this medication.
  • rifampin, rifadin, rifadin-r, clarithromycin.

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Erectile Dysfunction and Pulmonary Hypertension

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